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As an example, silica nanoparticles conjugated with dopamine selectively deliver antioxidants to dopaminergic neurons in vitro (89)
demonstrated a 29% higher drug uptake than non-targeted liposomes and a superior impact on disease delay when delivered by the intracerebroventricular route in ALS mice (124, 125)
PMID: 19876078
Thus, there is little evidence that citicoline treatment is efficacious for patients with cerebrovascular disease
Effect of aflatoxin metabolism and DNA adduct formation on hepatocellular carcinoma among chronic hepatitis B carriers in Taiwan.Journal of Hepatology;YuM
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